The 8 Best Nitric Oxide Supplements of 2025, Reviewed by Registered Dietitians

Transparent Labs Nitric Oxide is a nitric oxide booster that gets straight to the point, earning our pick for the best overall nitric oxide supplement. Its heavy-hitter ingredient is a hearty dose of NO3-T, a patented combination of arginine nitrate and betaine nitrate. Each serving provides 1,250 milligrams (mg) of arginine nitrate and 1,000mg of betaine nitrate. And while there’s very little research available for NO3-T, research shows that combining the two nitrates increases the body’s nitrate stores, supporting a stable, long-lasting production of nitric oxide for your workout. (2) 

Another ingredient, 250mg of L-glutathione, may help manage oxidative stress and encourage healthy blood flow. (3) And those 200mg of vitamin C? They increase the antioxidant content of the nutrition supplement and support nitrate absorption, so it can do its thing in nitric oxide production. (4)

This nitric oxide supplement is in capsule form, requiring four capsules per serving. If you’re not a fan of taking pills, this might be a deal breaker. Transparent Labs Nitric Oxide is highlighted as a pre-workout supplement, but you can take it anytime to help promote blood flow. If you’re taking Nitric Oxide to get a muscle pump before your workout, Transparent Labs recommends taking it 30-45 minutes before exercise on an empty stomach. 

Each 30-serving container costs $44.99 when ordered as a one-time purchase, costing around $1.50 per serving. However, you can arrange a delivery subscription for a $5 savings and free shipping, bringing the cost to $1.27 per serving. This is pretty average for nitric oxide-supporting products, earning it a 4 out of 5 score for price. 

Of course, in true Transparent Labs fashion, their Nitric Oxide supplement is third-party tested and Informed Choice certified. As a registered dietitian, I’m a fan of companies that send their supplements for third-party testing. The FDA doesn’t regulate dietary supplements, so I love to see brands go the extra mile to monitor their product’s purity and safety.  

One of our favorite nitric oxide supplements on Amazon right now is Jacked Factory’s Nitro Surge. Nitro Surge might be the most straightforward formula of their many different pre-workouts, making it an excellent option for those who want a good muscle pump without questionable ingredients. And with Prime shipping, it can be at your doorstep in as little as two days.

Nitro Surge supports nitric oxide production thanks to its citrulline content. Each scoop provides 3g of L-citrulline, which might be enough for those new to pre-workout supplements to cash in on nitric oxide benefits. However, Jacked Factory recommends that those with experience with this type of supplement should take two scoops for maximum results. We must agree, as research shows that 6-8g of citrulline is most effective for increasing blood flow. (10) You’ll need two scoops to hit clinically-researched doses, but one member of the BarBend team, a certified personal trainer thinks this makes it ideal for newbies.

“Being able to choose one or two scoops is good for someone starting out with pre-workouts,” they say. “It won’t give you those wild tingles or insane feeling that some other pre-workouts might.”

Unfortunately, those who do need 2 scoops to get the job done will have to pay a pretty penny — $1.73 for that higher dose serving. According to BarBend editorial member Matt Cummings, it might be worth the cost. “I usually work out in the morning, but I tried Nitro Surge in the early afternoon and definitely felt jacked up and ready to go,” he says.

“After about 10 seconds of shaking, it mixes up smoothly,” he says, rating its solubility 5 out of 5. “If you leave it sitting, of course it will settle a bit, but I just give it a quick shake before each sip.”

Nitro Surge comes in 16 flavors, including Arctic White, Black Cherry, and even Sour Peach Rings. See ya later, flavor fatigue! “I tried the Strawberry Margarita, which is available on Amazon, and I loved it,” our other tester says, giving the taste a 5 out of 5. “I could see myself drinking this at a pool, it’s so delicious.”

Another factor to consider is the artificial sweetener used in the formula. Nitro Surge uses sucralose, which may cause gastrointestinal distress in some people and leave an artificial aftertaste for most. Considering that you have to consume two scoops to get clinically based doses and that the product uses sucralose as a sweetener, we gave Nitro Surge a 3.5 out of 5 for its formulation. 

And while we love how accessible Nitro Surge is in both taste and retail availability, we’d be remiss not to mention that it doesn’t undergo any third-party testing for purity and safety. It scored a 1 out of 5 for third-party testing. Competitive athletes, especially those who may be subjected to drug testing, should keep that in mind.

Sometimes, mixing yet another powder supplement is the last thing you want to do, so you turn to capsules. However, not all capsule nitric oxide supplements are created equal. Nutricost’s Nitric Oxide Booster Capsules took home the title for best nitric oxide pills. While you have to take three capsules to get the maximum dose, that’s still far less than other nitric oxide pills on the market. 

Nutricost aims to improve blood flow and enhance exercise performance with its Nitric Oxide Booster Capsules. Improved blood flow translates to reduced fatigue, improved endurance, and improved recovery times. 

Each serving of Nitric Oxide Booster contains a blend of key ingredients, including L-arginine and L-citrulline, which work together to increase vasodilation and muscle pump. Unfortunately, each ingredient is included in very small amounts. Each serving provides just 1,500mg of arginine and 750mg of L-citrulline in various forms, earning its formulation a 2.5 out of 5 score in my book. My thinking is, if you’re going to invest in a supplement and trust it in your system, you want it to be backed by science. 

[Related: Best Citrulline Supplements]

Each bottle of capsules contains 60 servings, or a two-month supply, of nitric oxide boosters for $19.95 or $0.33 per serving. While the minimal doses of each ingredient might be to thank for its extremely low price, we can’t help but praise the affordability that Nutricost offers in this product. 

Although more than one dose of a three-capsule serving doesn’t sound ideal, if you need to bump your intake with multiple doses, it’s still more affordable than many other nitric oxide supplements. Plus, even at such an affordable cost, Nutricost is able to send its Nitric Oxide Booster Capsules for third-party testing, giving you peace of mind when taking the supplement.

Transparent Labs Bulk Black might be the answer if you want to streamline your pre-workout routine, as it acts as an all-in-one pre-workout and nitric oxide booster. With a hefty dose of citrulline malate combined with other ingredients designed to support vascular health and blood flow, Transparent Labs Bulk Black is no joke. Plus, each serving contains 275mg of caffeine, giving you a little pep in your step before you hit the gym. Compared to other pre-workout supplements, 275mg is a hefty dose of caffeine — roughly the same amount as three cups of coffee. Bulk Black may not be ideal if you’re sensitive to caffeine or prone to caffeine jitters.

Bulk Black also provides research-backed doses of nitric oxide boosting compounds — 8g of citrulline malate and 4g of beta-alanine. These compounds earned Bulk Black a 4.5 out of 5 for its formulation, as research shows us that adequate doses of citrulline malate and beta-alanine are 6-8g and 4-6g, respectively. (10) 

Still, this is a pre-workout supplement, so it may not bring a good pump to everyone. Our tester felt like they could lift harder but didn’t notice any significant muscle pumps, giving it a 3 out of 5 for overall experience. “I didn’t experience a pump, but I did notice tingles running up and down my arms for a good 30 to 45 minutes,” they said. 

Each tub of Bulk Black comes with 30 servings for $54.99, or $1.83 per serving. While that’s on the higher end of what we like to see nitric oxide supplements sell for, you are getting a lot for your money. Plus, you can set up a delivery subscription for a $6 savings and free shipping.   

Bulk Black is offered in seven delicious flavors, including Cherry Kiwi, Blue Raspberry, Peach Mango, Sour Gummy, Black Cherry, Watermelon Peach, and Blueberry Pomegranate. Our tester tried Blue Raspberry and found the taste to be a little underwhelming, rating that flavor a 3 out of 5. “It tastes a little watered down. I’d describe it more as a hint of blue raspberry. Maybe with less water, the flavor would be more potent,” they say.

“If you prefer pre-workouts that aren’t crazy sweet, this is the one for you,” they add. “It just has kind of a weird aftertaste.” Furthermore, there isn’t an unflavored option out of all those unique flavors. These creative flavors may not be conducive to mixing with other supplements or ingredients. 

Why We Like It

But what about those who want to improve their blood flow before a workout without consuming copious amounts of caffeine? That’s where the best non-stim pre-workouts come into play, and we think Legion Pulse Caffeine-Free Pre-Workout is a good fit for the job. It contains a clinically-based dose of citrulline malate and no caffeine.

Each 2-scoop serving contains a research-backed dose of 8 g of citrulline malate, higher than many competing nitric oxide supplements. Along with its positive effects on blood flow and muscle endurance, Legion Pulse can also improve strength, reduce fatigue, and increase power. Each scoop of Pulse contains beta-alanine, betaine anhydrous, and alpha-GPC.

“Usually I go with pre-workouts with caffeine,” one of our testers says, rating its overall effects 4.5 out of 5. “I’ve always been skeptical of non-stim options, but not anymore. The beta-alanine in Pulse gives me the same pump as others with stimulants.”

Of course, all these benefits don’t come cheap. Legion Pulse rivals Transparent Labs Bulk Black and Onnit Total Nitric Oxide for the most expensive nitric oxide supplement. Each container has 20 servings, costing $39.99 or $2 per serving. However, you can sign up for a delivery subscription for a small savings. 

Legion Pulse Caffeine-Free is available in eight unique flavors, including Arctic Blast, Blue Raspberry, Fruit Punch, Tropical Punch, Grape, Green Apple, Sour Candy, and Strawberry Kiwi. Unfortunately, there isn’t an unflavored option, so you have to be mindful about stacking supplement flavors. Another member of our team likes the seasonal pink lemonade flavor, giving it a 5 out of 5 for taste and stating, “I wouldn’t call it sour at all, but it is sweet. I usually water it down a bit so the flavor isn’t overwhelming.”

Legion recommends mixing two scoops of this pre-workout in 8-12 ounces of water approximately 30 minutes before hitting the gym to get maximum results. Then, you can wait for the clinically dosed ingredients to do their thing. As far as solubility goes, our tester reports no issues. “There weren’t any major clumps or noticeable grittiness after mixing, which was a huge plus for me. I hate a sludgy mixture at the bottom of the cup.”

Even without the caffeine, our tester noticed that their pump came with tingles, but nothing alarming. And for those of you reading this and wishing it did contain caffeine, you’re in luck! Legion offers its Pulse Pre-Workout in a caffeinated version that contains a whopping 350mg of caffeine. Just keep in mind that consuming 350mg of caffeine in your pre-workout is like drinking four cups of coffee before you hit the gym.

Why We Like It

Onnit Total Nitric Oxide caught our attention in our search for the best nitric oxide supplement for improving blood circulation. It’s packed with L-arginine nitrate and L-citrulline, two compounds linked to cardiovascular function. (6) Each serving provides 1.4 g of arginine nitrate and 3 g of L-citrulline, but its circulation support doesn’t stop there. It also contains Careflow Mango Fruit Powder, which has been linked to improved endothelial Nitric Oxide Synthase (eNOS) activity, a necessary pathway for blood circulation. (7)

My only hesitation with the supplement’s ingredient list is its proprietary blend. Total Nitric Oxide contains a proprietary blend of beetroot, grape seed, apple, and acerola cherry extracts. While the extracts themselves aren’t alarming, I prefer to know exactly how much of each ingredient is in each serving. We give the formulation a 3.5 out of 5 score, plus one of our testers, a certified personal trainer, isn’t blown away by its effects. “I do feel a tiny bit more focused,” they say. “But without any stimulant, it’s struggles to help me get going for an early morning workout.”

BarBend‘s testers weren’t too thrilled with the flavor, either. “I use the Harvest Fruit flavor and the beet is very strong,” they say, rating the taste a 3 out of 5. “It tastes very natural, which I don’t mind but I think may not be the case for the average shopper.”

Onnit recommends taking one scoop of their Total Nitric Oxide with 8 ounces of water up to twice daily, which may be less than convenient for some. Unfortunately, Onnit’s Nitric Oxide may be a budget buster compared to other nitric oxide boosters. When ordering as a one-time purchase, each tub costs $39.99. However, you can set up a delivery subscription for a 15 percent savings. At up to $2 per serving, it’s one of the most expensive options on this list, earning a 2 out of 5 score for its price per serving. Still, you get what you pay for as it’s third-party tested and Informed-Sport certified. 

Total Nitric Oxide boasts many purported benefits, including improved recovery, muscle-building support, reduced fatigue, and improved blood pressure. Our tester rates the overall effects a 3 out of 5, though. “I’d say I get a decent pump, but not much stronger or better than another standard pre-workout supplement,” they say.

But if you’re in the business of stacking supplements, this nitric oxide boosting supplement can also be combined with Onnit’s Total Strength & Performance to further improve blood flow and skin-splitting pumps. 

Plus, while Onnit Total Nitric Oxide may be more expensive than its competition, it comes with a 90-day money-back guarantee. If it wasn’t a fit for you, simply reach out to Onnit’s customer service for a full refund. 

Why We Like It

In our search for the best nitric oxide supplements, we knew we needed to find something to fit the specific needs of our bodybuilder friends. Enter SNAP Supplements Nitric Oxide. This product has a natural, organic formula with zero artificial sweeteners or dyes, which is a bonus for bodybuilders looking to prepare for a competition.

Each container comes with 30 servings. Additionally, each scoop provides organic beet root powder, organic pomegranate juice powder, and red spinach extract.

This formula also packs a good amount of vital vitamins and minerals. One serving packs 100% of your daily vitamin B3 value, 416% of your daily vitamin B12 value, and 3% of your daily recommended potassium value.

We like the simplicity of this formula, however, it isn’t the most budget-friendly. One 30-serving container costs $49.95, which is about $1.66 per serving. We had to give this product cost a 3 out of 5 rating, as there are definitely more budget-friendly products on this list. Though, you can subscribe to recurring deliveries and save 15%.

Why We Like It

Beetroot, with all its health benefits, has stepped into the spotlight and stolen the health and wellness show. Researchers have linked beetroot supplementation with improved markers for athletic performance, but its claim to fame continues to be its effects on overall health. Beetroot is often called a functional food for its role in improving blood lipids, blood glucose levels, and, our favorite, blood pressure. (5) And since KOS Organic Beet Root Powder contains organic beetroot powder and only organic beetroot powder, it earns our pick for the best nitric oxide supplement for blood pressure.

In my work as a dietitian, I like to prioritize whole foods first and then turn to supplements to bridge the gap between your nutritional needs and your dietary intake. Typically, the best nitric oxide foods are a great option because it’s rare to find a supplement that takes the same approach — but KOS hit the nail on the head in that regard. KOS kept this product simple, with only one ingredient — USDA organic beetroot powder. However, it’s unclear how much beetroot powder is actually in each serving, so we gave KOS Organic Beet Root Powder a 4 out of 5 for its formulation. And if you want your nitric oxide supplement to multitask, you may need to try another option on the list with more active ingredients.

Just one scoop of this organic, non-GMO, nitrate-rich beetroot supplement can improve blood pressure through its effects on vasodilation. With improved vasodilation comes decreased diastolic blood pressure. (5) Thanks to the beetroot, each scoop of this powder contains about 15 calories, 4 grams (g) of carbohydrates, and no protein or fat. Plus, it can be added to your favorite dish or beverage, making it convenient to incorporate a nitric oxide booster into your routine. 

You can snag a 90-serving container of this straightforward beet supplement for around $29.99 or approximately $0.33 per serving. As the most budget-friendly option on our list, it scored a 5 out of 5 for its price per serving. Unfortunately, that low price tag doesn’t allow for third-party testing — something to keep in mind if you’re a competitive athlete who undergoes drug testing.