The 6 Best Probiotic Supplements of 2024

Bacteria get a bad rap, but not all bacteria are actually bad for you. Your gut microbiome consists of trillions of beneficial bacteria called probiotics. Probiotics are involved in everything from helping you digest your food to absorbing the kinds of nutrients you can get from the best multivitamins. Having a healthy, balanced gut biome is key to having a strong immune system, maintaining a healthy metabolism, and regulating your mood and energy levels. (1) You can bolster your body’s probiotics by eating fermented foods, like yogurt and sauerkraut, but a probiotic supplement can give you the extra boost your gut might need.

Probiotic supplements can come in many forms, from probiotic capsules to greens powders. And they can also include additional ingredients like prebiotics (the foods probiotics eat), micronutrients, and digestive enzymes. If you’re looking for a probiotic to help solve digestive issues, boost your immunity, or just improve your overall wellness, the options can be overwhelming. To help you out, we looked for and tested a wide range of options to find the best probiotic supplements for various needs — these are our favorites.

The 6 Best Probiotic Supplements of 2024

• Best Probiotic Supplement Overall: Transparent Labs Gut Health Probiotic
• Best Probiotic Supplement for Digestion: Onnit Gut Health with Probiotics
• Best Probiotic Supplement for Bloating: Ritual Synbiotic+
• Best Probiotic for Weight Loss: Sports Research Probiotic
• Best Probiotic and Prebiotic: Seed Daily Synbiotic
• Best Probiotic Greens Supplement: Athletic Greens AG1

Editor’s note: The content on BarBend is meant to be informative in nature, but it shouldn’t take the place of advice and/or supervision from a medical professional. The opinions and articles on this site are not intended to diagnose, prevent, and/or treat health problems. Speak with your physician if you have any concerns or before beginning any new workout regime.

Best Probiotic Supplement Overall: Transparent Labs Gut Health Probiotic

If you’re looking for the most bang for your buck, Transparent Labs’ Gut Health Probiotics is the way to go. With 100 billion colony-forming units (CFU) per dose, you’ll be hard-pressed to find a more potent dose. And it doesn’t just have a huge dose, Gut Health also offers various different strains — there are 10 different strains of probiotics here, offering a variety of potential benefits that range from improving gut health to strengthening immunity. (2)(3)

While most supplements provide CFU counts in the low billions, the 100 billion that Transparent Labs Gut Health Probiotics provides is the largest dose we’ve seen. Plus, it comes in capsule form, which makes it easy to take or stack with other supplements. The capsules are vegan, so no worries if you are avoiding animal products (besides the bacteria, of course). And at about $1.50 per serving, it’s a bargain, especially when you consider the dosage. 

[Related: Best Probiotic Supplements for Women]

Best Probiotic Supplement for Digestion: Onnit Gut Health with Probiotics

While probiotics on their own can help improve digestive health, some people may be looking for some extra help. In addition to five different probiotic strains to potentially help with digestion, Onnit Total Gut Health also packs 900mg of Jerusalem artichoke and 600mg of dandelion root, both of which are soluble fibers that can help move food through the digestive system. (4) These fibers also act as prebiotics, helping to feed the 10 billion CFU of probiotics that Onnit delivers to your system. 

Total Gut Health also offers a digestive enzyme blend that includes betaine, which can help your body break down food. (5) It should be noted that while these do come in convenient packets, each serving is seven pills. And while you can take them throughout the day, Onnit recommends taking them all at once, which might be a problem for people who don’t like taking pills. 

Best Probiotic Supplement for Bloating: Ritual Synbiotic+

Ritual’s offering stands out for its three-in-one approach to maintaining gut health. The outer casing of the capsule is made up of prebiotic fibers, which not only help the probiotic tablet inside stay intact until it can reach the colon, but also provide a food supply for them when they get there. The probiotic tablet inside contains 11 billion CFU that include the strains Lacticaseibacillus rhamnosus, which, among other potential benefits, may reduce the occurrence of bloating. (6) Finally, the probiotic tablet is surrounded by a short-chain fatty acid called tributyrin, which can also help keep bloating to a minimum. (7) 

Tributyrin is also what’s known as a postbiotic, a naturally occurring metabolic result of a healthy gut biome, and it can help support the growth of beneficial gut bacteria. (8) Ritual’s website is very transparent, tracing all of its ingredients back to the source, and while this isn’t one of the cheaper probiotic supplements out there, they do offer a money-back guarantee if you’re not satisfied with your results. 

Best Probiotic for Weight Loss: Sports Research Probiotic

If you’re looking for a probiotic for weight loss, Sports Research Probiotic is worth your consideration. In addition to a probiotic blend, it offers a 60-milligram fiber inulin blend which can promote feelings of fullness and “may support a healthy metabolism, blood sugar control, and the fight against inflammation,” says our expert reviewer, Chelsea Rae Bourgeois, MS, RDN, LD. Side effects, taste, and smell all scored a 5 out of 5 with our tester.

Inulin, a prebiotic fiber, is also associated with increased levels of Bifidobacterium, a probiotic that can help support digestion and has been shown in some studies to help lower body fat. (10)(17) This fiber also serves as a food source for the 60 billion CFU blend of probiotics, which can help the 12 strains of good bacteria thrive in your gut to help you maintain a healthy digestive system.

If you want to take specific quantities of bacteria strains, you won’t be able to track how much you’re consuming with this product. “While it’s not uncommon in a probiotic supplement, the bacteria strains are in a proprietary blend, so you can’t be sure how much of each is in the product,” says Bourgeois.

Lastly, this product is shelf-stable, which means you can store it at room temperature in your cupboard. However, the label does recommend keeping this bottle in the refrigerator, so you may want to keep it there instead.

Best Probiotic and Prebiotic: Seed Daily Synbiotic

Probiotics add new microbes to your gut, while prebiotics provide those microbes with a tasty snack to help them thrive within your gut. (18)  With 24 strains of probiotics and a prebiotic formulation made from punicalagin — sourced from pomegranates — Seed Daily Synbiotic is our choice of the best probiotic and prebiotic supplement.  Taste, smell, and side effects scored a 5 out of 5 with our tester. 

“[It] contains an impressive blend of probiotic and prebiotic bacteria to support gut and overall health,” says our expert reviewer, Chelsea Rae Bourgeois, MS, RDN, LD, who scored the formulation a 4.5 out of 5. “I like that Seed breaks down their bacteria blends into categories of health benefits. Each serving of Synbiotic contains 53.6 AFU of various bacteria, each offering research-backed benefits. And because they have been freeze-dried, you don’t have to refrigerate the product.”

[Related: Best Prebiotic Foods]

The 2-in-1 capsule features a prebiotic outer capsule and a probiotic inner capsule, which helps keep the prebiotics from getting digested and broken down in your stomach acid. This way they’re able to make it to the large intestine and colon, where they help balance out your gut’s microbiome.

The biggest sticking point for this supplement is that you’ll need to enroll in a subscription where this supplement is delivered every month, every three months, or bi-annually.

While everything that Seed promises seems great, there’s no way to be sure that what’s promised is what you’re getting. “Seed doesn’t mention third-party testing on their website,” said Bourgeois. “I wish this product was tested by an independent lab for purity.”

Best Probiotic Greens Supplement: Athletic Greens AG1

If you want to get in your probiotics, your vitamins, and your greens all in one fell swoop, Athletic Greens AG1 has you covered. In addition to 7.2 billion CFU of probiotics, this greens powder contains 75 different vitamins and minerals, including B vitamins, vitamin C, vitamin A, folate, and zinc. AG1 also includes a superfood blend, an antioxidant blend, and a digestive enzyme blend as well. 

And while most greens powders have that “freshly-mowed lawn” taste to them, AG1 has a vanilla and pineapple flavor that adds some sweetness and definitely cuts down on the grassy taste. “I’ve never been a fan of greens powders because the taste is awful,” our tester says. “But this is kind of sweet. I actually looked forward to waking up and starting my day with this one.” At over $2.50 per serving, this is on the higher end of the price spectrum, but with such a packed ingredients list, you’re getting a lot for your money. 

Read our full Athletic Greens AG1 Review. 

Benefits of Probiotic Supplements

Most people tend to focus on how probiotics can help with digestive issues, which makes sense because they do their work in your digestive tract. But the potential benefits of probiotics go far beyond digestion — it may also help reduce inflammation, improve your mental health, and even help keep your energy levels up. 

Aid in Digestion

Adding a probiotic supplement may help improve your body’s ability to absorb nutrients as well as reduce digestive problems, like gas and bloating. Having an abundance of healthy bacteria in your system can help fend off any harmful bacteria that you may consume with your food and help maintain a healthy gut microbiome. (11)

Reducing Inflammation

Chronic inflammation can lead to a wide range of health issues like heart disease, cancer, and Alzheimer’s disease, and it’s so prevalent that the World Health Organization lists chronic inflammatory diseases as the most common cause of death in the world. Studies have suggested that probiotics may reduce inflammation in subjects. (12) 

Improving Mental Health

As counterintuitive as it may seem, there is evidence that higher levels of unhealthy bacteria in the gut may increase individuals’ levels of stress. Some studies have found that probiotics, as they can help lower the amount of unhealthy bacteria in the gut, may also help improve mental health in the process. (13)

Higher Energy Levels

Another issue that may arise when unhealthy bacteria thrive in the gut microbiome is higher levels of fatigue. Studies on endurance athletes suggest that probiotics can help stave off fatigue and raise energy levels by maintaining a healthy gut biome. (14) 

How We Chose The Best Probiotic Supplements

There’s no shortage of probiotic supplements on the market, and the right one for each person can vary depending on your needs and goals. So we looked at a few factors that are common across a broad range of needs based on our supplement testing methodology.

Dosage

Finding the right dosage of probiotics is key. For most people (especially beginners), you’ll want somewhere between five and 10 billion CFU, so we included quite a few with that dosage. Other people may want or need more, so we added supplements with higher amounts, up to 100 billion CFU. 

But if you’re new to probiotics, you may not want to go right to the higher-dosed supplements. Taking high doses of probiotics may lead to gastric issues like bloating or gas, so be sure to start on the lower end and then work your way up if need be. 

Ingredients

Many probiotic supplements are stand-alone supplements, but others come in the form of multivitamins, greens powders, and even fiber supplements. If you already have a greens powder or multivitamin that you like, a standalone supplement may be the right option.

But if you’re looking to combine your supplements, you may want to check out some of the probiotics on this list that have added fiber, vitamins, or minerals. 

Price

We won’t sugar-coat it — probiotics can be expensive. Some of the higher-dosed supplements can cost up to $3 per serving. But if you’re looking for a more moderate (yet still effective) dose, you can pay anywhere from $0.50 to $1.50 per serving. We included probiotics on all ends of the pricing spectrum to help you find one that will fit your budget. 

How Much Do Probiotic Supplements Cost? 

Long story short: Probiotics can cost a lot. If you’re looking for a supplement that has a more robust ingredients list, you may be looking at $2-$2.50 or more per serving. But you don’t have to spend a ton to find an effective probiotic supplement. There are options on this list that cost under a dollar but still have effective dosages. Most often, these less expensive options will be on the more basic side — essentially a capsule that contains several billion CFU. If you’re willing to shell out a little more, you’ll usually find some with unique features that will help the probiotics pass through the stomach intact or with added vitamins, minerals, or enzymes. 

What to Consider Before Buying a Probiotic Supplement

From how much to take to what additional ingredients you want, there are a lot of factors to consider when deciding on the right probiotic supplement for you. We’ve laid out some of the most important ones below. 

Dosage

Figuring out how many CFUs are right for you can be tricky. Too little, and you may not notice any effects. Too much, and you may experience gastrointestinal discomfort. For most people, 10 to 20 billion CFUs is plenty, but those who have never tried probiotics should probably stay closer to five. (15) If you have serious stomach issues or 10 to 20 CFU doesn’t seem to be helping, a higher dose might be a good idea. 

Form 

Probiotic supplements are most commonly found in either powder or capsule form. Powders are ideal for people who are averse to taking pills and they mix easily with smoothies or water, but they can be a pain to take with you if you travel.

If you don’t have any problems with swallowing pills, the capsule can be more convenient since you don’t need to do any mixing or shaking, and they can go pretty much anywhere you go. 

Price

A supplement won’t do you any good if you can’t afford it. Fortunately, probiotics vary widely in price — you can find effective supplements for well under a dollar per serving, while probiotics with additional ingredients or mixed in green powders can be on the middle to higher end of the price spectrum. Be sure to align your needs with your budget, and you’ll find the right one for you. 

Added Ingredients

If you’re looking for a probiotic to solve a specific issue like bloating or bad digestion, it may be worth it to seek out a supplement that has additional ingredients like digestive enzymes or added fiber. Also, if you’d like an all-in-one supplement, you may want to seek out a greens powder that mixes probiotics with vitamins and minerals, so you can take care of your daily supplements all at once. 

Best Probiotic Supplements FAQs

Resources

1. Thursby E, Juge N. Introduction to the human gut microbiota. Biochem J. 2017 May 16;474(11):1823-1836. doi: 10.1042/BCJ20160510. PMID: 28512250; PMCID: PMC5433529.
2. Dempsey E, Corr SC. Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives. Front Immunol. 2022 Apr 6;13:840245. doi: 10.3389/fimmu.2022.840245. PMID: 35464397; PMCID: PMC9019120.
3. Yan F, Polk DB. Probiotics and immune health. Curr Opin Gastroenterol. 2011 Oct;27(6):496-501. doi: 10.1097/MOG.0b013e32834baa4d. PMID: 21897224; PMCID: PMC4006993.
4. Sawicka B, Skiba D, Pszczółkowski P, Aslan I, Sharifi-Rad J, Krochmal-Marczak B. Jerusalem artichoke (Helianthus tuberosus L.) as a medicinal plant and its natural products. Cell Mol Biol (Noisy-le-grand). 2020 Jun 25;66(4):160-177. PMID: 32583794.
5. Wang, H., Li, S., Fang, S., Yang, X., & Feng, J. (2018). Betaine Improves Intestinal Functions by Enhancing Digestive Enzymes, Ameliorating Intestinal Morphology, and Enriching Intestinal Microbiota in High-salt stressed Rats. Nutrients, 10(7). https://doi.org/10.3390/nu10070907
6. Ceccherini C, Daniotti S, Bearzi C, Re I. Evaluating the Efficacy of Probiotics in IBS Treatment Using a Systematic Review of Clinical Trials and Multi-Criteria Decision Analysis. Nutrients. 2022 Jun 28;14(13):2689. doi: 10.3390/nu14132689. PMID: 35807868; PMCID: PMC9268703.
7. Mocanu V, Park H, Dang J, Hotte N, Thiesen A, Laffin M, Wang H, Birch D, Madsen K. Timing of Tributyrin Supplementation Differentially Modulates Gastrointestinal Inflammation and Gut Microbial Recolonization Following Murine Ileocecal Resection. Nutrients. 2021 Jun 17;13(6):2069. doi: 10.3390/nu13062069. PMID: 34204288; PMCID: PMC8233937.
8. Cresci G, Nagy LE, Ganapathy V. Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury. JPEN J Parenter Enteral Nutr. 2013 Nov;37(6):763-74. doi: 10.1177/0148607113486809. Epub 2013 Apr 29. PMID: 23630018; PMCID: PMC3818407.
9. https://www.nih.gov/news-events/nih-research-matters/health-benefits-dietary-fibers-vary
10. Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, Balzarini M, Montino F, Orsello M, Pagliarulo M, Sartori M, Tari R, Sforza F, Capurso L. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S30-4. doi: 10.1097/MCG.0b013e3181ee31c3. PMID: 20697291.
11. Kechagia M, Basoulis D, Konstantopoulou S, Dimitriadi D, Gyftopoulou K, Skarmoutsou N, Fakiri EM. Health benefits of probiotics: a review. ISRN Nutr. 2013 Jan 2;2013:481651. doi: 10.5402/2013/481651. PMID: 24959545; PMCID: PMC4045285.
12. Carvalho BM, Saad MJ. Influence of gut microbiota on subclinical inflammation and insulin resistance. Mediators Inflamm. 2013;2013:986734. doi: 10.1155/2013/986734. Epub 2013 Jun 12. PMID: 23840101; PMCID: PMC3694527.
13. Messaoudi M, Lalonde R, Violle N, Javelot H, Desor D, Nejdi A, Bisson JF, Rougeot C, Pichelin M, Cazaubiel M, Cazaubiel JM. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr. 2011 Mar;105(5):755-64. doi: 10.1017/S0007114510004319. Epub 2010 Oct 26. PMID: 20974015.
14. Mach N, Fuster-Botella D. Endurance exercise and gut microbiota: A review. J Sport Health Sci. 2017 Jun;6(2):179-197. doi: 10.1016/j.jshs.2016.05.001. Epub 2016 May 10. PMID: 30356594; PMCID: PMC6188999.
15. https://www.aafp.org/pubs/afp/issues/2008/1101/p1073.html
16.  Figueroa-González I, Cruz-Guerrero A, Quijano G (2011) The Benefits of Probiotics on Human Health. J Microbial Biochem Technol S1:003. doi:10.4172/1948-5948.S1-003
17. Sung, H. K., Youn, S. J., Choi, Y., Eun, S. W., Shin, S. M. (2022). Body Fat Reduction Effect of Bifidobacterium breve B-3: A Randomized, Double-Blind, Placebo Comparative Clinical Trial. Nutrients. 15(1):28.
18. Davani-Davari, D., Negahdaripour, M., Karimzadeh, I., Seifan, M., Mohkam, M., Masoumi, S. J., Berenjian, A., Ghasemi, Y. (2019). Prebiotics: Definition, Types, Sources, Mechanisms, and Clinical Applications. Foods. 8(3):92.